Neuroimaging and Staging: Do Disparate Mental Illnesses Have Distinct Neurobiological Trajectories?

Abstract

Integration of brain structural information into prognostic and treatment formulation is key for achieving an all-encompassing biopsychosocial approach in psychiatry. Uncovering biological markers of specific mental illnesses, specific illness stages and of remission, may help further our understanding of the aetiology and precipitators of certain types of psychopathologies, identify central neurobiological processes as distinct from epiphenomena, validate boundaries of clinical groups, and potentially aid in predicting response to treatment. This book chapter reviewed the current structural neuroimaging evidence in three prominent mental illness domains: schizophrenia-spectrum, bipolar and ..